Flights from Denver to Knoxville – Direct & connecting routes
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DEN to TYS – All flight route options from Denver International, Colorado, USA to Mc Ghee Tyson, Tennessee, USA. These flights are operated by 6 different airlines. Fly non-stop or choose from 8 different connecting flights. The shortest flight time is 2 hours and 39 minutes. See the full flight schedule and time table, including departure times, airlines and stopover details to find the best option for you.
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Denver to Knoxville flights
There are over 11 airlines and as many as 320 flights every week to this destination. You can fly non-stop to Knoxville (TYS) from Denver (DEN) with Frontier Airlines, United Airlines or Allegiant Air but if a stopover option suits you better you can choose to fly via Chicago, Minneapolis or any other of the 8 alternatives with connectiing airports.
Denver to Knoxville with Frontier Airlines
Frontier Airlines has non-stop every Thursday or Sunday at 11:00 am, 1:00 pm or 2:00 pm.
With Delta Air Lines
If you fly to Knoxville from Denver with Delta Air Lines you will do a stopover in Minneapolis. Delta Air Lines is a member of SkyTeam.
Distance & flight times: Denver International to Mc Ghee Tyson
The shortest flight time between DEN and TYS is 2 hours and 48 minutes.
Via | Total flight time | Layover time | Distance |
---|---|---|---|
Direct | 2h 48m | - | 1166 miles (1876 km) |
ORD Chicago | 5h 28m | 1h 5m | 1368 miles (2201 km) |
MSP Minneapolis | 5h 34m | 1h 15m | 1478 miles (2378 km) |
DFW Dallas | 5h 36m | 2h 9m | 1418 miles (2282 km) |
ATL Atlanta | 5h 43m | 1h 12m | 1355 miles (2180 km) |
OKC Oklahoma City | 6h 4m | 2h 9m | 1265 miles (2035 km) |
CLT Charlotte | 6h 13m | 46m | 1519 miles (2444 km) |
IAH Houston | 6h 17m | 1h 42m | 1640 miles (2639 km) |
DTW Detroit | 6h 25m | 2h 43m | 1572 miles (2529 km) |


