Flights from Des Moines to Charlotte – Direct & connecting routes
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DSM to CLT – All flight route options from Des Moines International, Iowa, USA to Charlotte Douglas International, North Carolina, USA. These flights are operated by 5 airlines. Fly non-stop with American Airlines or choose from 8 different transit flights. The shortest flight time is 2 hours and 23 minutes. See the full flight schedule and time table, including departure times, airlines and stopover details to find the best option for you.
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Des Moines to Charlotte flights
With over 219 flights every week and 9 different airlines you have a wide range of options. You can fly non-stop to Charlotte (CLT) from Des Moines (DSM) with American Airlines but if a stopover option suits you better you can choose to fly via Saint Louis, Chicago or any other of the 8 alternatives with connectiing airports.
Des Moines to Charlotte with American Airlines
You can fly non-stop every weekday with flights departing from 6:00 am to 6:00 pm. You can also catch a transit flight via Chicago or Washington. American Airlines is a member of the air alliance OneWorld.
With Southwest Airlines
If you fly from Des Moines with Southwest Airlines you will do a stopover in Saint Louis, STL before reaching Charlotte. This flight trip will take 3 hours and 45 minutes and you can fly every Friday with departures at 05:45, 08:35 or 16:45.
Distance & flight times: Des Moines International to Charlotte Douglas
The shortest flight time between DSM and CLT is 2 hours and 23 minutes.
Via | Total flight time | Layover time | Distance |
---|---|---|---|
Direct | 2h 23m | - | 818 miles (1316 km) |
STL Saint Louis | 3h 45m | 45m | 837 miles (1347 km) |
ORD Chicago | 5h 11m | 1h 13m | 901 miles (1450 km) |
DCA Washington | 5h 28m | 30m | 1232 miles (1982 km) |
ATL Atlanta | 5h 50m | 2h 59m | 974 miles (1567 km) |
MSP Minneapolis | 5h 52m | 2h 0m | 1167 miles (1878 km) |
PHL Philadelphia | 5h 59m | 1h 3m | 1424 miles (2291 km) |
DTW Detroit | 6h 15m | 2h 6m | 1038 miles (1670 km) |
ROC Rochester | 9h 24m | 2h 48m | 1403 miles (2257 km) |


