Flights from Des Moines to Los Angeles – Direct & connecting routes
Non-stop airlines Connecting flights Show map Price search
DSM to LAX – All flight route options from Des Moines International, Iowa, USA to Los Angeles International, California, USA. These flights are operated by 6 airlines. Fly non-stop with American Airlines or choose from 12 different transit flights. The shortest flight time is 4 hours and 25 minutes. See the full flight schedule and time table, including departure times, airlines and stopover details to find the best option for you.
Find the best prices on hotels and car rental near Los Angeles
We got great deals on hotels and car rentals near the airport.
Des Moines to Los Angeles flights
There are over 13 airlines and as many as 277 flights every week to this destination. You can fly non-stop to Los Angeles (LAX) from Des Moines (DSM) with American Airlines but if a stopover option suits you better you can choose to fly via Phoenix, Las Vegas or any other of the 12 alternatives with connectiing airports.
Des Moines to Los Angeles with American Airlines
You can fly non-stop every weekday with flights departing at 15:20 or 16:00. You can also catch a transit flight via Phoenix or Dallas. American Airlines is a member of the air alliance OneWorld.
Note Non-stop flights with American Airlines will begin in Oct 2025.
With Southwest Airlines
Distance & flight times: Des Moines International to LAX
The shortest flight time between DSM and LAX is 4 hours and 25 minutes.
Via | Total flight time | Layover time | Distance |
---|---|---|---|
Direct | 4h 25m | - | 1452 miles (2336 km) |
PHX Phoenix | 6h 1m | 2h 43m | 1525 miles (2454 km) |
LAS Las Vegas | 6h 18m | 45m | 1457 miles (2344 km) |
DEN Denver | 6h 23m | 1h 18m | 1456 miles (2343 km) |
DFW Dallas | 6h 50m | 1h 52m | 1867 miles (3004 km) |
ORD Chicago | 7h 23m | 2h 34m | 2049 miles (3297 km) |
STL Saint Louis | 7h 35m | 2h 50m | 1857 miles (2988 km) |
MSP Minneapolis | 7h 44m | 2h 50m | 1774 miles (2854 km) |
OAK Oakland | 8h 15m | 1h 30m | 1883 miles (3030 km) |
SFO San Francisco | 8h 58m | 1h 9m | 1893 miles (3046 km) |
ELP El Paso | 9h 20m | 2h 30m | 1693 miles (2724 km) |
SJC San Jose | 10h 21m | 1h 0m | 1846 miles (2970 km) |
SAT San Antonio | 10h 55m | 2h 55m | 2091 miles (3364 km) |

