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Flights from Des Moines to Knoxville – Airlines & connecting routes

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DSM to TYS flights and routes map DSM to TYS – All flight route options from Des Moines International, Iowa, USA to Mc Ghee Tyson, Tennessee, USA. These flights are operated by 4 different airlines through 5 different connections. The shortest flight time is 4 hours and 46 minutes. See the full flight schedule and time table, including departure times, airlines and stopover details to find the best option for you.

From
To
USA DSM Des Moines Des Moines, IA, USA
USA TYS Mc Ghee Tyson, TN, USA
DSM
Des Moines
USADes Moines, IA, USA
Mc Ghee Tyson
USAKnoxville, TN, USA
TYS

1 stop route options with the same airline:

Duration

Via Chicago ORD
1 stop with United Airlines. 2-4 flights per day.

SHOW SCHEDULE
4h 25m

Via Chicago ORD
1 stop with United Airlines.
4h 25m
2-4 flights per day.
SHOW SCHEDULE
Via Minneapolis MSP
1 stop with Delta Air Lines. 0-2 flights per day.

SHOW SCHEDULE
4h 45m

Via Minneapolis MSP
1 stop with Delta Air Lines.
4h 45m
0-2 flights per day.
SHOW SCHEDULE
Via Atlanta ATL
1 stop with Delta Air Lines. 2-4 flights per day.

SHOW SCHEDULE
4h 46m

Via Atlanta ATL
1 stop with Delta Air Lines.
4h 46m
2-4 flights per day.
SHOW SCHEDULE
Via Chicago ORD
1 stop with American Airlines. 2-3 flights per day.

SHOW SCHEDULE
4h 53m

Via Chicago ORD
1 stop with American Airlines.
4h 53m
2-3 flights per day.
SHOW SCHEDULE
Via Detroit DTW
1 stop with Delta Air Lines. 0-1 flights per day.

SHOW SCHEDULE
4h 59m

Via Detroit DTW
1 stop with Delta Air Lines.
4h 59m
0-1 flights per day.
SHOW SCHEDULE
Via Charlotte CLT
1 stop with American Airlines. 2-3 flights per day.

SHOW SCHEDULE
5h 17m

Via Charlotte CLT
1 stop with American Airlines.
5h 17m
2-3 flights per day.
SHOW SCHEDULE
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1 stop route options with codeshare or different airlines:

Duration

Via Chicago ORD With American Airlines & United Airlines 2-3 flights per day.

SHOW SCHEDULE
5h 16m

Via Chicago ORD
5h 16m
With American Airlines & United Airlines 2-3 flights per day.
SHOW SCHEDULE
SELECT DATE & CHECK PRICE
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Des Moines to Knoxville flights

With over 120 flights every week and 5 different airlines you have a wide range of options. While flying to Knoxville from Des Moines you will be doing a stopover in Minneapolis, Atlanta or any other of the 5 alternatives with flight connections.

Are there any non-stop flights from DSM to TYS?

There are no direct or non-stop flights from Des Moines International, DSM to Mc Ghee Tyson, TYS.

Des Moines to Knoxville with United Airlines

If you fly from Des Moines with United Airlines you will do a stopover in Chicago, ORD before reaching Knoxville. This flight trip will take 4 hours and 25 minutes and you can fly every weekday with departures between 6:00 am and 3:00 pm. United Airlines is a Star Alliance member.

Distance & flight times: Des Moines International to Mc Ghee Tyson

The shortest flight time between DSM and TYS is 4 hours and 45 minutes.

ViaTotal flight timeLayover timeDistance
MSP Minneapolis4h 45m1h 23m1029 miles (1656 km)
ATL Atlanta4h 46m58m898 miles (1445 km)
ORD Chicago4h 53m1h 42m776 miles (1249 km)
DTW Detroit4h 59m2h 50m981 miles (1578 km)
CLT Charlotte5h 17m2h 47m995 miles (1601 km)
The flight times and layover times in the table above are approximate and may vary depending on flight number, aircraft, airline, weather, and time of day.DSM-TYS flight routesDes Moines to Knoxville flight routes illustrated on a map.
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Des Moines - Knoxville route map and flight paths
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The fastest way to fly from Des Moines (DSM) to Knoxville (TYS) is via Minneapolis and it will take about 4 hours and 45 minutes. The second fastest route is via Atlanta and will take 4 hours and 46 minutes.

You can fly with Delta Air Lines or American Airlines from Des Moines to Knoxville.

The flight time between Des Moines (DSM) and Mc Ghee Tyson (TYS) via Minneapolis St Paul International, MSP is 4 hours and 45 minutes.

No. But you can still purchase a 1 stop flight via Minneapolis, Atlanta or any other route to Knoxville (TYS).

A codeshare agreement means that cooperating airlines are able to sell seats on each other’s flights. This means that you are able to travel to more destinations than your airline of choice normally offers. Codeshare flights are also beneficial because of the seamless transits you can get with connecting flights from the same airline. The downside of choosing a codeshare flight can be that you in some cases can’t upgrade codeshare flights or use elite benefits.

A connecting or transit flight means that you reach your final destination through two or more flights – in other words a non-direct flight. You will change to a new aircraft after your first flight, this may include moving to another terminal at the airport aswell. The time required to transfer passengers and luggage between flights is called Minimum Connecting Time (MCT) and are always taken into account here on Flightroutes.com.

If you bought your whole flight on a single ticket, the airline will book you on the next available connecting flight.

With connecting flights, checked in luggage is most commonly forwarded to your final destination when buying a single ticket for both flights.

If you miss your connecting flight due to circumstances outside your control such as your first flight being delayed, you should turn to your airline who will provide you with a seat on the next available flight. This is usually done free of charge, and only applies if you purchased your trip as one ticket. If the next connecting flight is the following day, the airline usually provides accommodation and meals.
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