Flights from Guayaquil to Medellin – Direct & connecting routes
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GYE to MDE – All flight route options from Simon Bolivar International, Ecuador to Jose Maria Cordova, Colombia. These flights are operated by 4 airlines. Fly non-stop with AVIANCA or choose from 3 different transit flights. The shortest flight time is 1 hour and 40 minutes. See the full flight schedule and time table, including departure times, airlines and stopover details to find the best option for you.
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Guayaquil to Medellin flights
With over 227 flights every week and 4 different airlines you have a wide range of options. You can fly non-stop to Medellin (MDE) from Guayaquil (GYE) with AVIANCA but if a stopover option suits you better you can choose to fly via Quito, Panama City or any other of the 3 alternatives with connectiing airports.
Guayaquil to Medellin with AVIANCA
You can fly non-stop every Monday, Wednesday or Friday at 1:00 pm, 2:00 pm or 4:00 pm. You can also catch a transit flight via Quito or Bogota. AVIANCA is a Star Alliance member.
With Copa Airlines
If you fly from Guayaquil with Copa Airlines you will do a stopover in Panama City, PTY before reaching Medellin. This flight trip will take 5 hours and 29 minutes and you can fly every weekday with departures between 4:00 am and 6:00 pm. Copa Airlines is a Star Alliance member.
Distance & flight times: Simon Bolivar International to Jose Maria Cordova
The shortest flight time between GYE and MDE is 1 hour and 40 minutes.
Via | Total flight time | Layover time | Distance |
---|---|---|---|
Direct | 1h 40m | - | 653 miles (1051 km) |
UIO Quito | 5h 0m | 2h 35m | 656 miles (1056 km) |
PTY Panama City | 5h 29m | 42m | 1107 miles (1781 km) |
BOG Bogota | 5h 45m | 1h 15m | 766 miles (1232 km) |


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From Guayaquil to Colombia
Below is a list of other destinations to Colombia from Simon Bolivar International with either direct flights or 1 stop connections.
From Ecuador to Medellin
Below is a list of other cities in Ecuador with flights to Medellin with either non-stop or connecting flights.