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Flights from Medellin to Santiago – Direct & connecting routes

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MDE to SCL flights and routes map MDE to SCL – All flight route options from Jose Maria Cordova, Colombia to Arturo Merino Benítez International Airport, Chile. These routes are operated by 5 airlines. Fly non-stop with AVIANCA or JetSMART, or choose from 4 different stopover flights. The shortest flight time is 5 hours and 55 minutes. See the full flight schedule and time table, including departure times, airlines and stopover details to find the best option for you.

From
To
Colombia MDE Jose Maria Cordova Medellin, Colombia
Chile SCL Arturo Merino Benítez Airport, Chile
MDE
Jose Maria Cordova
ColombiaMedellin, Colombia
Arturo Merino Benítez Airport
ChileSantiago, Chile
SCL
2 direct routes found »
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10 routes with 1 stop found »
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Non-stop route options:

Duration

AVIANCA
Non-stop with AVIANCA. 0-1 flights per day.

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5h 55m

AVIANCA
Non-stop with AVIANCA.
5h 55m
0-1 flights per day.
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JetSMART
Non-stop with JetSMART. 0-1 flights per day.
Begins in 1/12

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6h 08m

Begins in 1/12
JetSMART
Non-stop with JetSMART.
6h 08m
0-1 flights per day.
Begins in 1/12
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1 stop route options with the same airline:

Duration

Via Lima LIM
1 stop with JetSMART. 1-2 flights per day.

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8h 57m

Via Lima LIM
1 stop with JetSMART.
8h 57m
1-2 flights per day.
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Via Lima LIM
1 stop with LATAM Airlines. 1-2 flights per day.

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9h 25m

Via Lima LIM
1 stop with LATAM Airlines.
9h 25m
1-2 flights per day.
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Via Bogota BOG
1 stop with LATAM Airlines. 1-3 flights per day.

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9h 51m

Via Bogota BOG
1 stop with LATAM Airlines.
9h 51m
1-3 flights per day.
LATAMAIRLINES.COM
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Via Bogota BOG
1 stop with AVIANCA. 7-9 flights per day.

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10h 10m

Via Bogota BOG
1 stop with AVIANCA.
10h 10m
7-9 flights per day.
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Via Bogota BOG
1 stop with JetSMART. 0-2 flights per day.
Begins in 2/12

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10h 32m

Begins in 2/12
Via Bogota BOG
1 stop with JetSMART.
10h 32m
0-2 flights per day.
Begins in 2/12
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Via Cali CLO
1 stop with JetSMART. 0-1 flights per day.
Only wednesdays

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10h 40m

Only wednesdays
Via Cali CLO
1 stop with JetSMART.
10h 40m
0-1 flights per day.
Only wednesdays
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Via Panama City PTY
1 stop with Copa Airlines. 7-9 flights per day.

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11h 18m

Via Panama City PTY
1 stop with Copa Airlines.
11h 18m
7-9 flights per day.
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1 stop route options with codeshare or different airlines:

Duration

Via Bogota BOG With AVIANCA & LATAM Airlines 4-5 flights per day.

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9h 43m

Via Bogota BOG
9h 43m
With AVIANCA & LATAM Airlines 4-5 flights per day.
LATAMAIRLINES.COM
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Via Lima LIM With AVIANCA & LATAM Airlines 0-1 flights per day.
Tue,Thu & Sat

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9h 46m

Tue,Thu & Sat
Via Lima LIM
9h 46m
With AVIANCA & LATAM Airlines 0-1 flights per day.
Tue,Thu & Sat
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Via Panama City PTY With AVIANCA & Copa Airlines 1-2 flights per day.

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11h 47m

Via Panama City PTY
11h 47m
With AVIANCA & Copa Airlines 1-2 flights per day.
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Find the best prices on hotels and car rental near Arturo Merino Benítez Airport

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Medellin to Santiago flights

With over 250 flights every week and 6 different airlines you have a wide range of options. You can fly non-stop to Santiago (SCL) from Medellin (MDE) with JetSMART or AVIANCA but if a stopover option suits you better you can choose to fly via Lima, Bogota or any other of the 4 alternatives with connectiing airports.

Medellin to Santiago with JetSMART

You can fly non-stop every Monday, Wednesday, Friday or Sunday with departure times at 13:13 or 14:13. You can also catch a transit flight via Lima or Bogota.

Note Non-stop flights with JetSMART will begin in Dec 2025.

With LATAM Airlines

If you choose to fly with LATAM Airlines from Medellin to Santiago you can make a transit either via Lima or via Bogota. The route via Lima is 26 minutes faster.

Distance & flight times: Jose Maria Cordova to Santiago International Airport

The shortest flight time between MDE and SCL is 6 hours and 8 minutes.

ViaTotal flight timeLayover timeDistance
Direct6h 8m-2770 miles (4457 km)
LIM Lima9h 25m4h 50m2810 miles (4521 km)
BOG Bogota10h 10m3h 14m2801 miles (4507 km)
CLO Cali10h 40m3h 53m2785 miles (4481 km)
PTY Panama City11h 18m1h 18m3331 miles (5360 km)
The flight times and layover times in the table above are approximate and may vary depending on flight number, aircraft, airline, weather, and time of day.MDE-SCL flight routesMedellin to Santiago flight routes illustrated on a map.
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Medellin - Santiago route map and flight paths
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From Medellin to Chile

Below is a list of other destinations to Chile from Jose Maria Cordova with either direct flights or 1 stop connections.

From Colombia to Santiago

Below is a list of other cities in Colombia with flights to Santiago with either non-stop or connecting flights.

You can fly non-stop from Medellin (MDE) to Santiago (SCL) with JetSMART or AVIANCA. The flight takes approximately 6 hours and 8 minutes. If you travel with a connecting flight instead, for example via Lima, the total flight time will be 9 hours and 25 minutes.

If you're interested in direct flights, JetSMART or AVIANCA is available. For flights with stopovers, LATAM Airlines, AVIANCA, JetSMART or Copa Airlines is also an option.

The flight time between Jose Maria Cordova (MDE) and Arturo Merino Benítez International Airport (SCL) is approximately 6 hours and 8 minutes. The distance between the two airports is 2801 miles (or 4507 kilometers).

Yes, you can fly non-stop to SCL from MDE with JetSMART or AVIANCA.

A codeshare agreement means that cooperating airlines are able to sell seats on each other’s flights. This means that you are able to travel to more destinations than your airline of choice normally offers. Codeshare flights are also beneficial because of the seamless transits you can get with connecting flights from the same airline. The downside of choosing a codeshare flight can be that you in some cases can’t upgrade codeshare flights or use elite benefits.

A connecting or transit flight means that you reach your final destination through two or more flights – in other words a non-direct flight. You will change to a new aircraft after your first flight, this may include moving to another terminal at the airport aswell. The time required to transfer passengers and luggage between flights is called Minimum Connecting Time (MCT) and are always taken into account here on Flightroutes.com.

If you bought your whole flight on a single ticket, the airline will book you on the next available connecting flight.

With connecting flights, checked in luggage is most commonly forwarded to your final destination when buying a single ticket for both flights.

If you miss your connecting flight due to circumstances outside your control such as your first flight being delayed, you should turn to your airline who will provide you with a seat on the next available flight. This is usually done free of charge, and only applies if you purchased your trip as one ticket. If the next connecting flight is the following day, the airline usually provides accommodation and meals.
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