Flights from Chicago to Buffalo – Direct & connecting routes
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MDW to BUF – All flight route options from Chicago Midway International, Illinois, USA to Buffalo Niagara International, New York, USA. These flights are operated by 2 airlines. Fly non-stop with Southwest Airlines or choose from 3 different transit flights. The shortest flight time is 1 hour and 25 minutes. See the full flight schedule and time table, including departure times, airlines and stopover details to find the best option for you.
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Chicago to Buffalo flights
With over 67 flights every week and 4 different airlines you have a wide range of options. You can fly non-stop to Buffalo (BUF) from Chicago (MDW) with Southwest Airlines but if a stopover option suits you better you can choose to fly via Detroit, Baltimore or any other of the 3 alternatives with connectiing airports.
Chicago to Buffalo with Southwest Airlines
You can fly non-stop every weekday with flights departing from 7:00 am to 10:00 pm. You can also take a connecting flight via Baltimore or Saint Louis.
With Delta Air Lines
If you fly from Chicago with Delta Air Lines you will do a stopover in Detroit, DTW before reaching Buffalo. This flight trip will take 4 hours and 44 minutes and you can fly every weekday with departures between 9:00 am and 6:00 pm. Delta Air Lines is a member of SkyTeam.
Distance & flight times: Midway International Airport to Buffalo Niagara International
The shortest flight time between MDW and BUF is 1 hour and 25 minutes.
Via | Total flight time | Layover time | Distance |
---|---|---|---|
Direct | 1h 25m | - | 469 miles (755 km) |
DTW Detroit | 4h 44m | 2h 21m | 470 miles (756 km) |
BWI Baltimore | 5h 25m | 1h 10m | 894 miles (1438 km) |
STL Saint Louis | 7h 45m | 2h 35m | 928 miles (1493 km) |

