Flights from Mexico City to Panama City – Direct & connecting routes
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MEX to PTY – All flight route options from Mexico City International Airport, Mexico to Tocumen International, Panama. These routes are operated by 3 airlines. Fly non-stop with Copa Airlines or Aeromexico, or choose from 5 different stopover flights. The shortest flight time is 3 hours and 44 minutes. See the full flight schedule and time table, including departure times, airlines and stopover details to find the best option for you.
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Mexico City to Panama City flights
With over 108 flights every week and 7 different airlines you have a wide range of options. You can fly non-stop to Panama City (PTY) from Mexico City (MEX) with Aeromexico or Copa Airlines but if a stopover option suits you better you can choose to fly via Guatemala City, San Pedro Sula or any other of the 5 alternatives with connectiing airports.
Mexico City to Panama City with Aeromexico
You can fly non-stop every weekday with flights departing at 08:40 or 08:55. Aeromexico is a member of SkyTeam.
Distance & flight times: Mexico City International Airport to Tocumen International
The shortest flight time between MEX and PTY is 3 hours and 52 minutes.
Via | Total flight time | Layover time | Distance |
---|---|---|---|
Direct | 3h 52m | - | 1506 miles (2423 km) |
GUA Guatemala City | 6h 19m | 2h 19m | 1508 miles (2426 km) |
SAP San Pedro Sula | 7h 26m | 2h 37m | 1517 miles (2441 km) |
SJO San Jose | 7h 31m | 4h 34m | 1529 miles (2460 km) |
CUN Cancun | 8h 15m | 2h 7m | 1773 miles (2853 km) |
MGA Managua | 10h 5m | 4h 19m | 1509 miles (2428 km) |


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From Mexico City to Panama
We have found another destination to Panama from Mexico City International Airport as well.
From Mexico to Panama City
Below is a list of other cities in Mexico with flights to Panama City with either non-stop or connecting flights.
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CUN Cancun Direct
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MTY Monterrey Direct
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GDL Guadalajara Direct
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NLU Mexico City Direct
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SJD San Jose Cabo Direct
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PVR Puerto Vallarta
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TIJ Tijuana
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BJX Leon/Guanajuato
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MZT Mazatlan
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QRO Queretaro