Flights from Mexico City to Santo Domingo – Direct & connecting routes
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MEX to SDQ – All flight route options from Mexico City International Airport, Mexico to Las Americas International, Dominican Republic. These flights are operated by 5 airlines. Fly non-stop with Aeromexico or choose from 2 different transit flights. The shortest flight time is 4 hours and 27 minutes. See the full flight schedule and time table, including departure times, airlines and stopover details to find the best option for you.
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Mexico City to Santo Domingo flights
With over 82 flights every week and 3 different airlines you have a wide range of options. You can fly non-stop to Santo Domingo (SDQ) from Mexico City (MEX) with Aeromexico or choose a connecting flight via Miami (MIA) or Panama City (PTY) if it suits you better.
Mexico City to Santo Domingo with Aeromexico
You can fly non-stop every weekday with flights departing at 00:15, 01:00 or 01:01. Aeromexico is a member of SkyTeam.
With American Airlines
If you fly from Mexico City with American Airlines you will do a stopover in Miami, MIA before reaching Santo Domingo. This flight trip will take 7 hours and 45 minutes and you can fly every weekday with departures at 5:00 am, 7:00 am or 10:00 am. American Airlines is a member of the air alliance OneWorld.
Distance & flight times: Mexico City International Airport to Las Americas International
The shortest flight time between MEX and SDQ is 4 hours and 27 minutes.
Via | Total flight time | Layover time | Distance |
---|---|---|---|
Direct | 4h 27m | - | 1931 miles (3107 km) |
MIA Miami | 7h 45m | 1h 40m | 2134 miles (3434 km) |
PTY Panama City | 8h 27m | 3h 16m | 2428 miles (3907 km) |


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From Mexico City to Dominican Republic
Below is a list of other destinations to Dominican Republic from Mexico City International Airport with either direct flights or 1 stop connections.
From Mexico to Santo Domingo
Below is a list of other cities in Mexico with flights to Santo Domingo with either non-stop or connecting flights.