Flights from Panama City to Madrid – Direct & connecting routes
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PTY to MAD – All flight route options from Tocumen International, Panama to Barajas, Spain. These routes are operated by 11 airlines. Fly non-stop with Air Europa or Iberia, or choose from 21 different stopover flights. The shortest flight time is 9 hours and 50 minutes. See the full flight schedule and time table, including departure times, airlines and stopover details to find the best option for you.
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Panama City to Madrid flights
There are over 23 airlines and as many as 488 flights every week to this destination. You can fly non-stop to Madrid (MAD) from Panama City (PTY) with Iberia or Air Europa but if a stopover option suits you better you can choose to fly via Bogota, Medellin or any other of the 21 alternatives with connectiing airports.
Panama City to Madrid with Iberia
You can fly non-stop every Wednesday, Thursday, Friday or Sunday with departure times at 17:20, 17:35 or 18:20. Iberia is a member of the air alliance OneWorld.
With AVIANCA
If you fly from Panama City with AVIANCA you will do a stopover in Bogota, BOG before reaching Madrid. This flight trip will take 13 hours and 35 minutes and you can fly every weekday with departures between 9:00 am and 3:00 am. AVIANCA is a Star Alliance member.
Distance & flight times: Tocumen International to Barajas
The shortest flight time between PTY and MAD is 10 hours and 5 minutes.
Via | Total flight time | Layover time | Distance |
---|---|---|---|
Direct | 10h 5m | - | 5097 miles (8201 km) |
BOG Bogota | 13h 35m | 3h 0m | 5489 miles (8832 km) |
MDE Medellin | 13h 36m | 2h 15m | 5352 miles (8611 km) |
UIO Quito | 13h 57m | 1h 34m | 6100 miles (9815 km) |
AMS Amsterdam | 14h 0m | 1h 15m | 6419 miles (10328 km) |
CDG Paris | 14h 10m | 1h 15m | 6075 miles (9775 km) |
SDQ Santo Domingo | 14h 13m | 3h 30m | 5102 miles (8209 km) |
MIA Miami | 14h 25m | 4h 0m | 5603 miles (9015 km) |
PUJ Punta Cana | 15h 7m | 4h 21m | 5098 miles (8203 km) |
BOS Boston | 15h 11m | 2h 22m | 5789 miles (9315 km) |
SJU San Juan | 15h 15m | 4h 33m | 5098 miles (8203 km) |
IAD Dulles | 15h 17m | 2h 36m | 5907 miles (9504 km) |
STI Santiago | 15h 34m | - | - |
GYE Guayaquil | 15h 41m | 2h 56m | 6411 miles (10315 km) |
SJO San Jose | 16h 0m | 4h 45m | 5647 miles (9086 km) |
JFK New York | 16h 8m | 4h 18m | 5820 miles (9364 km) |
ATL Atlanta | 16h 35m | 3h 59m | 6086 miles (9792 km) |
SAL San Salvador | 16h 45m | 3h 20m | 6140 miles (9879 km) |
ORD Chicago | 17h 0m | 4h 34m | 6560 miles (10555 km) |
CUN Cancun | 17h 11m | - | - |
EWR New York | 17h 20m | - | - |
FRA Frankfurt | 18h 10m | 4h 20m | 6568 miles (10568 km) |


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From Panama City to Spain
Below is a list of other destinations to Spain from Tocumen International with either direct flights or 1 stop connections.
From Panama to Madrid
Below is a list of other cities in Panama with flights to Madrid with either non-stop or connecting flights.