Flights from Fort Myers to San Francisco – Direct & connecting routes
Non-stop airlines Connecting flights Show map Price search
RSW to SFO – All flight route options from Southwest Florida International Airport, Florida, USA to San Francisco International, California, USA. These flights are operated by 7 airlines. Fly non-stop with United Airlines or choose from 19 different transit flights. The shortest flight time is 6 hours and 23 minutes. See the full flight schedule and time table, including departure times, airlines and stopover details to find the best option for you.
Find the best prices on hotels and car rental near San Francisco
We got great deals on hotels and car rentals near the airport.
Fort Myers to San Francisco flights
There are over 20 airlines and as many as 204 flights every week to this destination. You can fly non-stop to San Francisco (SFO) from Fort Myers (RSW) with United Airlines but if a stopover option suits you better you can choose to fly via Denver, Nashville or any other of the 19 alternatives with connectiing airports.
Fort Myers to San Francisco with United Airlines
You can fly non-stop every weekday with flights departing at 10:00. You can also catch a transit flight via Denver or Houston. United Airlines is a Star Alliance member.
Note Non-stop flights with United Airlines will begin in Dec 2025.
With American Airlines
If you fly to San Francisco from Fort Myers with American Airlines you will do a stopover in Charlotte. American Airlines is a member of the air alliance OneWorld.
Distance & flight times: Southwest Florida International Airport to SFO Airport
The shortest flight time between RSW and SFO is 6 hours and 19 minutes.
Via | Total flight time | Layover time | Distance |
---|---|---|---|
Direct | 6h 19m | - | 2490 miles (4006 km) |
DEN Denver | 8h 25m | 1h 41m | 2585 miles (4159 km) |
BNA Nashville | 8h 30m | 1h 40m | 2701 miles (4346 km) |
CLT Charlotte | 8h 34m | 46m | 2909 miles (4681 km) |
ATL Atlanta | 8h 39m | 1h 6m | 2665 miles (4288 km) |
DFW Dallas | 8h 53m | 2h 24m | 2490 miles (4006 km) |
ORD Chicago | 9h 4m | 55m | 2980 miles (4795 km) |
IAH Houston | 9h 6m | 2h 25m | 2505 miles (4031 km) |
STL Saint Louis | 9h 8m | 40m | 2726 miles (4386 km) |
MDW Chicago | 9h 15m | 50m | 2973 miles (4784 km) |
DTW Detroit | 9h 15m | 3h 0m | 3178 miles (5113 km) |
CLE Cleveland | 9h 19m | 1h 4m | 3201 miles (5150 km) |
MSP Minneapolis | 9h 26m | 1h 46m | 3020 miles (4859 km) |
LAS Las Vegas | 9h 50m | 1h 0m | 2493 miles (4011 km) |
PHX Phoenix | 10h 20m | 2h 40m | 2528 miles (4068 km) |
MCI Kansas City | 10h 39m | 34m | 2665 miles (4288 km) |
SLC Salt Lake City | 10h 48m | 2h 10m | 2594 miles (4174 km) |
LAX Los Angeles | 12h 32m | 1h 33m | 2586 miles (4161 km) |
PDX Portland | 12h 41m | 45m | 3162 miles (5088 km) |
SAN San Diego | 12h 42m | 1h 26m | 2621 miles (4217 km) |

