Flights from Fort Myers to San Francisco – Direct & connecting routes
Non-stop airlines Connecting flights Show map Price search
RSW to SFO – All flight route options from Southwest Florida International Airport, Florida, USA to San Francisco International, California, USA. These flights are operated by 7 airlines. Fly non-stop with United Airlines or choose from 19 different transit flights. The shortest flight time is 6 hours and 19 minutes. See the full flight schedule and time table, including departure times, airlines and stopover details to find the best option for you.
Find the best prices on hotels and car rental near San Francisco
We got great deals on hotels and car rentals near the airport.
Fort Myers to San Francisco flights
There are over 21 airlines and as many as 231 flights every week to this destination. You can fly non-stop to San Francisco (SFO) from Fort Myers (RSW) with United Airlines but if a stopover option suits you better you can choose to fly via Saint Louis, Dallas or any other of the 20 alternatives with connectiing airports.
Fort Myers to San Francisco with United Airlines
You can fly non-stop every weekday with flights departing at 10:00. You can also catch a transit flight via Cleveland or Houston. United Airlines is a Star Alliance member.
Note Non-stop flights with United Airlines will begin in Dec 2025.
With Frontier Airlines
If you fly from Fort Myers with Frontier Airlines you will do a stopover in Denver, DEN before reaching San Francisco. This flight trip will take 8 hours and 36 minutes and you can fly every day of the week except Mondays with departures .
Distance & flight times: Southwest Florida International Airport to SFO Airport
The shortest flight time between RSW and SFO is 6 hours and 19 minutes.
Via | Total flight time | Layover time | Distance |
---|---|---|---|
Direct | 6h 19m | - | 2490 miles (4006 km) |
STL Saint Louis | 8h 20m | 1h 50m | 2726 miles (4386 km) |
DFW Dallas | 8h 31m | 40m | 2490 miles (4006 km) |
DEN Denver | 8h 36m | - | - |
ATL Atlanta | 8h 48m | 2h 19m | 2665 miles (4288 km) |
CLE Cleveland | 8h 54m | 1h 4m | 3201 miles (5150 km) |
IAH Houston | 8h 57m | 2h 14m | 2505 miles (4031 km) |
MSP Minneapolis | 9h 6m | 51m | 3020 miles (4859 km) |
SDF Louisville | 9h 18m | - | - |
DTW Detroit | 9h 27m | 1h 16m | 3178 miles (5113 km) |
DAL Dallas | 9h 45m | 55m | 2490 miles (4006 km) |
CLT Charlotte | 9h 47m | 1h 5m | 2909 miles (4681 km) |
MDW Chicago | 10h 25m | 2h 25m | 2973 miles (4784 km) |
ORD Chicago | 10h 29m | 1h 9m | 2980 miles (4795 km) |
MCI Kansas City | 11h 35m | 1h 11m | 2665 miles (4288 km) |
SAN San Diego | 12h 10m | 2h 20m | 2621 miles (4217 km) |
LAX Los Angeles | 12h 16m | 1h 45m | 2586 miles (4161 km) |
SLC Salt Lake City | 12h 21m | - | - |
PHX Phoenix | 13h 10m | 2h 26m | 2528 miles (4068 km) |
SNA Santa Ana | 13h 47m | - | - |
LAS Las Vegas | 14h 54m | - | - |

