Flights from Fort Myers to Knoxville – Airlines & connecting routes
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RSW to TYS – All flight route options from Southwest Florida International Airport, Florida, USA to Mc Ghee Tyson, Tennessee, USA. These flights are operated by American Airlines & Delta Air Lines through 2 different flight connections. The shortest flight time is 4 hours and 18 minutes. See the full flight schedule and time table, including departure times, airlines and stopover details to find the best option for you.
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Fort Myers to Knoxville flights
With over 39 flights every week and 2 different airlines you have a wide range of options. While flying to Knoxville from Fort Myers you will be doing a stopover in either Atlanta (ATL) or Charlotte (CLT).
Are there any non-stop flights from RSW to TYS?
There are no direct or non-stop flights from Southwest Florida International Airport, RSW to Mc Ghee Tyson, TYS.
Fort Myers to Knoxville with Delta Air Lines
If you fly from Fort Myers with Delta Air Lines you will do a stopover in Atlanta, ATL before reaching Knoxville. This flight trip will take 4 hours and 18 minutes and you can fly every weekday with departures from 5:00 am to 7:00 pm. Delta Air Lines is a member of SkyTeam.
Distance & flight times: Southwest Florida International Airport to Mc Ghee Tyson
The shortest flight time between RSW and TYS is 4 hours and 18 minutes.
Via | Total flight time | Layover time | Distance |
---|---|---|---|
ATL Atlanta | 4h 18m | 1h 1m | 671 miles (1080 km) |
CLT Charlotte | 4h 55m | 2h 45m | 782 miles (1258 km) |

