Flights from Santiago to Guayaquil – Direct & connecting routes
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SCL to GYE – All flight route options from Arturo Merino Benítez International Airport, Chile to Simon Bolivar International, Ecuador. These flights are operated by LATAM Airlines. You can either fly non-stop to Guayaquil or with one stop via Lima. The shortest flight time is 5 hours and 23 minutes. See the full flight schedule and time table, including departure times, airlines and stopover details to find the best option for you.
Other flight options
Check out these routes. They have daily flights from Arturo Merino Benítez International Airport and connections to Guayaquil:
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Santiago to Guayaquil flights
There are over 2 and approximately 20 flights every week. You can fly non-stop to Guayaquil (GYE) from Santiago (SCL) with LATAM Airlines or opt for a connecting flight via Lima (LIM).
Santiago to Guayaquil with LATAM Airlines
You can fly non-stop every weekday with flights departing at 23:50, 23:56 or 00:45. You also have the option to do a transit flight via Lima.
Distance & flight times: Santiago International Airport to Simon Bolivar International
The shortest flight time between SCL and GYE is 5 hours and 23 minutes.
Via | Total flight time | Layover time | Distance |
---|---|---|---|
Direct | 5h 23m | - | 2249 miles (3619 km) |
LIM Lima | 8h 0m | 1h 50m | 2249 miles (3619 km) |


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From Santiago to Ecuador
Below is a list of other destinations to Ecuador from Arturo Merino Benítez International Airport with either direct flights or 1 stop connections.
From Chile to Guayaquil
Below is a list of other cities in Chile with flights to Guayaquil with either non-stop or connecting flights.