Flights from Saint Louis to San Diego – Direct & connecting routes
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STL to SAN – All flight route options from Saint Louis Airport, Missouri, USA to San Diego International Airport, California, USA. These flights are operated by 7 airlines. Fly non-stop with Southwest Airlines or choose from 19 different transit flights. The shortest flight time is 4 hours. See the full flight schedule and time table, including departure times, airlines and stopover details to find the best option for you.
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Saint Louis to San Diego flights
There are over 20 airlines and as many as 727 flights every week to this destination. You can fly non-stop to San Diego (SAN) from Saint Louis (STL) with Southwest Airlines but if a stopover option suits you better you can choose to fly via Phoenix, Denver or any other of the 19 alternatives with connectiing airports.
Saint Louis to San Diego with Southwest Airlines
You can fly non-stop every weekday with flights departing from 5:00 am to 9:00 pm. You can also catch a transit flight via Phoenix or Oklahoma City.
With Frontier Airlines
If you fly to San Diego from Saint Louis with Frontier Airlines you will do a stopover in Las Vegas.
Distance & flight times: Saint Louis Airport to San Diego International Airport
The shortest flight time between STL and SAN is 4 hours.
Via | Total flight time | Layover time | Distance |
---|---|---|---|
Direct | 4h 0m | - | 1562 miles (2513 km) |
PHX Phoenix | 5h 41m | 1h 37m | 1571 miles (2528 km) |
DEN Denver | 5h 58m | 1h 33m | 1628 miles (2619 km) |
SLC Salt Lake City | 6h 31m | 1h 18m | 1789 miles (2879 km) |
DFW Dallas | 6h 32m | 40m | 1727 miles (2779 km) |
OKC Oklahoma City | 6h 40m | 40m | 1603 miles (2579 km) |
IAH Houston | 6h 40m | 2h 17m | 1978 miles (3183 km) |
MSP Minneapolis | 6h 44m | 2h 13m | 1988 miles (3199 km) |
MCI Kansas City | 6h 48m | 2h 45m | 1575 miles (2534 km) |
DAL Dallas | 6h 58m | 2h 30m | 1733 miles (2788 km) |
LAS Las Vegas | 7h 10m | 2h 45m | 1635 miles (2631 km) |
OMA Omaha | 7h 20m | 2h 35m | 1660 miles (2671 km) |
BNA Nashville | 7h 20m | 2h 25m | 2029 miles (3265 km) |
MDW Chicago | 7h 30m | 45m | 1986 miles (3195 km) |
AUS Austin | 7h 30m | 2h 55m | 1893 miles (3046 km) |
HOU Houston | 7h 30m | 1h 40m | 2009 miles (3232 km) |
TUL Tulsa | 7h 35m | 1h 25m | 1592 miles (2562 km) |
FAT Fresno | 7h 40m | 45m | 1925 miles (3097 km) |
ORD Chicago | 7h 52m | 2h 41m | 1988 miles (3199 km) |
SAT San Antonio | 9h 23m | 2h 30m | 1923 miles (3094 km) |


