Flights from Saint Louis to Knoxville – Airlines & connecting routes
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STL to TYS – All flight route options from Saint Louis Airport, Missouri, USA to Mc Ghee Tyson, Tennessee, USA. These flights are operated by 4 different airlines through 3 different connections. The shortest flight time is 4 hours and 26 minutes. See the full flight schedule and time table, including departure times, airlines and stopover details to find the best option for you.
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Saint Louis to Knoxville flights
With over 175 flights every week and 3 different airlines you have a wide range of options. While flying to Knoxville from Saint Louis you will be doing a stopover in Chicago, Atlanta or any other of the 3 alternatives with flight connections.
Are there any non-stop flights from STL to TYS?
There are no direct or non-stop flights from Saint Louis Airport, STL to Mc Ghee Tyson, TYS.
Saint Louis to Knoxville with Delta Air Lines
If you fly from Saint Louis with Delta Air Lines you will do a stopover in Atlanta, ATL before reaching Knoxville. This flight trip will take 4 hours and 26 minutes and you can fly every weekday with departures from 6:00 am to 7:00 pm. Delta Air Lines is a member of SkyTeam.
Distance & flight times: Saint Louis Airport to Mc Ghee Tyson
The shortest flight time between STL and TYS is 4 hours and 10 minutes.
Via | Total flight time | Layover time | Distance |
---|---|---|---|
ORD Chicago | 4h 10m | 1h 51m | 736 miles (1184 km) |
ATL Atlanta | 4h 26m | 2h 42m | 638 miles (1027 km) |
CLT Charlotte | 5h 0m | 1h 0m | 754 miles (1213 km) |

