Flights from Knoxville to Charleston – Airlines & connecting routes
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TYS to CHS – All flight route options from Mc Ghee Tyson, Tennessee, USA to Charleston Afb International, South Carolina, USA. These flights are operated by American Airlines & Delta Air Lines through 2 different flight connections. The shortest flight time is 3 hours and 57 minutes. See the full flight schedule and time table, including departure times, airlines and stopover details to find the best option for you.
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Knoxville to Charleston flights
With over 81 flights every week and 2 different airlines you have a wide range of options. While flying to Charleston from Knoxville you will be doing a stopover in either Charlotte (CLT) or Atlanta (ATL).
Are there any non-stop flights from TYS to CHS?
There are no direct or non-stop flights from Mc Ghee Tyson, TYS to Charleston Afb International, CHS.
Knoxville to Charleston with American Airlines
If you fly from Knoxville with American Airlines you will do a stopover in Charlotte, CLT before reaching Charleston. This flight trip will take 3 hours and 57 minutes and you can fly every weekday with departures from 5:00 am to 8:00 pm. American Airlines is a member of the air alliance OneWorld.
Distance & flight times: Mc Ghee Tyson to Charleston Afb International
The shortest flight time between TYS and CHS is 3 hours and 57 minutes.
Via | Total flight time | Layover time | Distance |
---|---|---|---|
CLT Charlotte | 3h 57m | 2h 40m | 346 miles (557 km) |
ATL Atlanta | 4h 12m | 37m | 411 miles (661 km) |

